25-OH Vitamin D Levels in Patients Admitted to Ankara Etlik Ihtisas Training and Research Hospital

Fatma Uçar 1 * , Mine Yavuz Taşlıpınar 1, Ayşe Özden Soydaş 1, Nurgül Özcan 1
More Detail
1 Etlik İhtisas Eğitim ve Araştırma Hastanesi Biyokimya Kliniği, Ankara
* Corresponding Author
EUR J BASIC MED SCI, Volume 2, Issue 1, pp. 12-15. https://doi.org/10.21601/ejbms/9169
Download Full Text (PDF)


The most important effect of vitamin D is on calcium homeostasis and bone health. 25 hydroxy vitamin D (25-OH D) level should be measured to evaluate Vitamin D levels. The aim of this study was to determine whether vitamin D deficiency in patients admitted to our hospital and to establish the difference between 25-OH Vitamin D levels according to gender and age groups. The 25-OH vitamin D levels of a general adult population admitted to our hospital between 01.12.2010-22.08.2011 were investigated retrospectively through the hospital information system. Participants who had chronic illnesses were excluded from the study. Subjects were classified according to age groups (n=513). When comparing the serum levels of 25-OH D, there was no statistically significant difference among the groups [18-39 years, 40-69 years and 70 years and older (p>0.05)] .Also there was no statistically significant difference between groups in terms of gender (p>0.05). Mean 25-OH vitamin D levels of patients admitted to our hospital were found below 30 ng / ml. We determined that the prevalence of vitamin D deficiency (cut off value:20 ng/ml ) was 51.8% and that of vitamin D insufficiency was 20.7% in the population investigated. In many studies of vitamin D deficiency in adults, the prevalence was higher, especially in the Middle East and Asian countries. Vitamin D insufficiency was found to be very common in the population investigated from Ankara. According to this definition, widespread vitamin D insufficiency has been identified in this population. Because of the potential association of limited exposure to sunlight in Ankara and dietary factors we believe that dietary support and vitamin D supplementation would be appropriate.


Uçar F, Yavuz Taşlıpınar M, Özden Soydaş A, Özcan N. 25-OH Vitamin D Levels in Patients Admitted to Ankara Etlik Ihtisas Training and Research Hospital. Eur J Basic Med Sci. 2012;2(1):12-5. https://doi.org/10.21601/ejbms/9169


  • Vogeser M. Quantification of circulating 25-hydroxyvitamin D by liquid chromatography-tandem mass spectrometry. Journal of Streoid Biochemistry&Moleculer Biology 2010; 121: 565-73.
  • Moy FM, Bulgiba A. High prevalence of vitamin D insufficiency and its association with obesity and metabolic syndrome among Malay adults in Kuala Lumpur, Malaysia. Public Health 2011; 11:735.
  • Meer IM, Middelkoop BJC, Boeke AJP, Lips P. Prevalence of vitamin D deficiency among Turkish, Moroccan, Indian and sub-Sahara African populations in Europe and their countries of origin: an overview. Osteoporos Int 2011; 22:1009-21.
  • Shea MK, Houston DK, Tooze JA, et al. Correlates and prevalence of insufficient 25-hydroxyvitamin D status in black and white older adults: The health, aging and body composition study. J Am Geriatr Soc 2011; 59:1165-74.
  • Mallah EM, Hamad MF, Elmanaseer MA, Qinna NA, et al. Plasma concentrations of 25-hydroxyvitamin D among Jordanians: Effect of biological and habitual factors on vitamin D status. Clinical Pathology 2011; 11:8.
  • Vu LH, Whiteman DC, Pols JC, Kimlin MG, Neale RE. Serum vitamin D levels in office workers in a subtropical climate. Photochemistry and Photobiology 2011; 87: 714-20.
  • Nanri A., Foo LH, Nakamura K, et al. Serum 25-hydroxyvitamin D concentrations and season-specific correlates in Japanese adults. J Epidemiol 2011; JE20100161.
  • Kaehler ST, Baumgartner H, Jeske M, et al. Prevalence of hypovitaminosis D and folate deficiency in healthy young female Austrian students in a health care profession. Eur J Nutr 2011; 11:281-5.
  • Lips P. Vitamin D status and nutrition in Europe and Asia. Journal of Steroid Biochemistry&Moleculer Biology 2007; 103:620-5.
  • Schoor MN, Lips P. Worldwide vitamin D status. Best Practice&Research Clinical Endocrinology&Metabolism 2011; 25:671-80.
  • Olson ML, Maalouf NM, Oden JD, White PC, Hutchison MR. Vitamin D deficiency in obese children and its relationship to glucose homeostasis. J Clin Endocrinol Metab 2012; 97(1):279-85.
  • Mansoor S, Habib A, Ghani F, et al. Prevalence and significance of vitamin D deficiency and insufficiency among apparently healthy adults. Clinical Biochemistry 2010; 43:1431-5.
  • Kaya T, Ulutaş Ö, Çavuşoğlu A, Aslanca D,et al. Sağlıklı postmenapozal kadınlarda serum 25(OH) vitamin-D düzeyi ve hiperparatroidi. Romatizma 2007; 22:20-3.
  • Burnand B, Sloutskis D, Gianoli F, et al. Serum 25-hydroxyvitamin D: distribution and determinants in the Swiss population. Am L Clin Nutr 1992; 56:537-42.
  • Akman AO, Tumer L, Hasanoğlu A, İlhan M, Caycı B. The frequency of vitamin D insufficiency in healthy children between 1 and 16 years of age in Turkey. Pediatr Int 2011; 53:968-73.
  • Yoon H, Park CS, Seo JY, Choi YS, Ahn YM. Clinical characteristics and prevalence of vitamin D insufficiency in children less than two years of age. Koren J Pediatr 2011; 54(7):298-303.
  • Harinarayan CV. Prevalence of vitamin D insufficiency in postmenopausal south Indian women. Osteoporos Int 2005; 16:397-402.
  • Ölmez D, Bober E, Büyükgebiz A, Cimrin D. The frequency of vitamin D insufficiency in healthy female adolescents. Acta Pediatrica 2006; 95:1266-9.
  • Hatun S, İslam Ö, Çizmecioğlu F, et al. Subclinical vitamin D deficiency is increased in adolescent girls who wear concealing clothing. J Nutr 2005; 135:218-22.